crazygazza, I always do, if you use the medium setting also drop the frame rate to 12 to match so you eliminate skipping. I find that the final conversion to AMV has a slight audio sync problem so I also adjust that.
Here are some settings to try, they include resize, brightness and contrast, hue and saturation, deinterlacing, frame rate adjustments and audio adjustments.
DOWNLOAD
You can load the file and all the settings to VDub by choosing File>Load processing settings....
The only thing I have not adjusted is the cropping if you want to remove any areas.